My site is a hobby project about the board game Hex, at http://hex.kosmanor.com/hex-bin/board, all hand-coded for CGI. This makes it slow, and I gather it's far from state-of-the-art these days. I'd like to add AJAX, and improve it in a way that still uses Python but does not have to start python up from scratch for each page. and also change from a hand-coded database to SQLite. I could use advice about what framework/toolset to use, and where to learn more.
I own Adobe Creative Suite 5 (including Dreamweaver), but I'm not married to using it, especially because it predates HTML5.